| Mon, Nov 2, 2026 |  vsWest Georgia WolvesWeek 1Wintrust Arena | Mon, Nov 2, 2026, 8:00 PM ET | Wintrust Arena |
| Thu, Nov 5, 2026 |  vsSouth Florida BullsWeek 1Wintrust Arena | Thu, Nov 5, 2026, 8:30 PM ET | Wintrust Arena |
| Mon, Nov 9, 2026 |  vsAlabama A&M BulldogsWeek 2Wintrust Arena | Mon, Nov 9, 2026, 9:00 PM ET | Wintrust Arena |
| Fri, Nov 13, 2026 |  @Northwestern WildcatsWeek 2Welsh-Ryan Arena | Fri, Nov 13, 2026, 12:00 AM ET | Welsh-Ryan Arena |
| Tue, Nov 17, 2026 |  vsMaryland Eastern Shore HawksWeek 3Wintrust Arena | Tue, Nov 17, 2026, 8:00 PM ET | Wintrust Arena |
| Tue, Nov 24, 2026 |  vsPurdue BoilermakersFort Myers Tip-Off - Beach DivisionSuncoast Credit Union Arena | Tue, Nov 24, 2026, 6:00 PM ET | Suncoast Credit Union Arena |
| Thu, Nov 26, 2026 |  vsPittsburgh PanthersFort Myers Tip-Off - Beach DivisionSuncoast Credit Union Arena | Thu, Nov 26, 2026, 7:00 PM ET | Suncoast Credit Union Arena |
| Tue, Dec 1, 2026 |  vsNorth Alabama LionsWeek 5Wintrust Arena | Tue, Dec 1, 2026, 8:00 PM ET | Wintrust Arena |
| Sat, Dec 5, 2026 |  vsSMU MustangsWeek 5Wintrust Arena | Sat, Dec 5, 2026, 5:30 PM ET | Wintrust Arena |
| Tue, Dec 8, 2026 |  vsMaine Black BearsWeek 6Wintrust Arena | Tue, Dec 8, 2026, 9:00 PM ET | Wintrust Arena |
| Sat, Dec 12, 2026 |  @Saint Louis BillikensWeek 6Chaifetz Arena | Sat, Dec 12, 2026, 6:30 PM ET | Chaifetz Arena |
| Sat, Dec 19, 2026 |  @St. John's Red StormWeek 7Madison Square Garden | Sat, Dec 19, 2026, 8:30 PM ET | Madison Square Garden |
| Tue, Dec 22, 2026 |  vsCanisius Golden GriffinsWeek 8Wintrust Arena | Tue, Dec 22, 2026, 8:00 PM ET | Wintrust Arena |
| Wed, Dec 30, 2026 |  vsSeton Hall PiratesWeek 9Wintrust Arena | Wed, Dec 30, 2026, 4:00 PM ET | Wintrust Arena |
| Sat, Jan 2, 2027 |  vsProvidence FriarsWeek 9Wintrust Arena | Sat, Jan 2, 2027, 2:00 PM ET | Wintrust Arena |
| Wed, Jan 6, 2027 |  @UConn HuskiesWeek 10M&T Bank Center at Gampel Pavilion | Wed, Jan 6, 2027, 6:30 PM ET | M&T Bank Center at Gampel Pavilion |
| Sat, Jan 9, 2027 |  vsButler BulldogsWeek 10Wintrust Arena | Sat, Jan 9, 2027, 4:00 PM ET | Wintrust Arena |
| Wed, Jan 13, 2027 |  @Creighton BluejaysWeek 11CHI Health Center Omaha | Wed, Jan 13, 2027, 9:00 PM ET | CHI Health Center Omaha |
| Sat, Jan 16, 2027 |  @Marquette Golden EaglesWeek 11Fiserv Forum | Sat, Jan 16, 2027, 1:30 PM ET | Fiserv Forum |
| Tue, Jan 19, 2027 | vsSt. John's Red StormWeek 12Wintrust Arena | Tue, Jan 19, 2027, 7:30 PM ET | Wintrust Arena |
| Fri, Jan 22, 2027 |  vsVillanova WildcatsWeek 12Wintrust Arena | Fri, Jan 22, 2027, 7:00 PM ET | Wintrust Arena |
| Sat, Jan 30, 2027 |  vsXavier MusketeersWeek 13Wintrust Arena | Sat, Jan 30, 2027, 2:00 PM ET | Wintrust Arena |
| Wed, Feb 3, 2027 |  @Georgetown HoyasWeek 14Capital One Arena | Wed, Feb 3, 2027, 8:30 PM ET | Capital One Arena |
| Sun, Feb 7, 2027 | @Seton Hall PiratesWeek 14Prudential Center | Sun, Feb 7, 2027, 2:30 PM ET | Prudential Center |
| Wed, Feb 10, 2027 | vsUConn HuskiesWeek 15Wintrust Arena | Wed, Feb 10, 2027, 8:30 PM ET | Wintrust Arena |
| Sat, Feb 13, 2027 | @Providence FriarsWeek 15Amica Mutual Pavilion | Sat, Feb 13, 2027, 12:00 PM ET | Amica Mutual Pavilion |
| Tue, Feb 16, 2027 | vsGeorgetown HoyasWeek 16Wintrust Arena | Tue, Feb 16, 2027, 9:00 PM ET | Wintrust Arena |
| Sat, Feb 20, 2027 | @Xavier MusketeersWeek 16Cintas Center | Sat, Feb 20, 2027, 3:00 PM ET | Cintas Center |
| Tue, Feb 23, 2027 | @Butler BulldogsWeek 17Hinkle Fieldhouse | Tue, Feb 23, 2027, 8:00 PM ET | Hinkle Fieldhouse |
| Sat, Feb 27, 2027 | vsCreighton BluejaysWeek 17Wintrust Arena | Sat, Feb 27, 2027, 7:00 PM ET | Wintrust Arena |
| Wed, Mar 3, 2027 | @Villanova WildcatsWeek 18Finneran Pavilion | Wed, Mar 3, 2027, 7:00 PM ET | Finneran Pavilion |
| Sat, Mar 6, 2027 | vsMarquette Golden EaglesWeek 18Wintrust Arena | Sat, Mar 6, 2027, 7:00 PM ET | Wintrust Arena |
DePaul Blue Demons Schedule 2026-2027: Dates, Times, TV and Results