| Mon, Nov 2, 2026 |  vsChattanooga MocsWeek 1KFC Yum! Center | Mon, Nov 2, 2026, 9:00 PM ET | KFC Yum! Center |
| Sat, Nov 7, 2026 |  vsMorehead State EaglesWeek 1KFC Yum! Center | Sat, Nov 7, 2026, 12:00 PM ET | KFC Yum! Center |
| Sun, Nov 15, 2026 |  @Memphis TigersWeek 2FedExForum | Sun, Nov 15, 2026, 1:00 PM ET | FedExForum |
| Thu, Nov 19, 2026 |  vsStetson HattersWeek 3KFC Yum! Center | Thu, Nov 19, 2026, 8:00 PM ET | KFC Yum! Center |
| Tue, Nov 24, 2026 |  vsTexas Tech Red RaidersPlayers Era 16Michelob ULTRA Arena | Tue, Nov 24, 2026, 8:00 PM ET | Michelob ULTRA Arena |
| Tue, Dec 1, 2026 |  vsTexas LonghornsACC/SEC Men's ChallengeKFC Yum! Center | Tue, Dec 1, 2026, 9:00 PM ET | KFC Yum! Center |
| Sat, Dec 5, 2026 |  vsMichigan WolverinesWeek 5Little Caesars Arena | Sat, Dec 5, 2026, 12:00 PM ET | Little Caesars Arena |
| Sat, Dec 12, 2026 |  @Kentucky WildcatsWeek 6Rupp Arena | Sat, Dec 12, 2026, 4:00 PM ET | Rupp Arena |
| Wed, Dec 16, 2026 |  vsLong Island University SharksWeek 7KFC Yum! Center | Wed, Dec 16, 2026, 9:00 PM ET | KFC Yum! Center |
| Sat, Dec 19, 2026 |  vsEastern Michigan EaglesWeek 7KFC Yum! Center | Sat, Dec 19, 2026, 1:30 PM ET | KFC Yum! Center |
| Wed, Dec 30, 2026 |  @Virginia Tech HokiesWeek 9Cassell Coliseum | Wed, Dec 30, 2026, 8:00 PM ET | Cassell Coliseum |
| Sat, Jan 2, 2027 |  vsStanford CardinalWeek 9KFC Yum! Center | Sat, Jan 2, 2027, 6:00 PM ET | KFC Yum! Center |
| Tue, Jan 5, 2027 |  vsNorth Carolina Tar HeelsWeek 10KFC Yum! Center | Tue, Jan 5, 2027, 9:00 PM ET | KFC Yum! Center |
| Sat, Jan 9, 2027 |  @SMU MustangsWeek 10Moody Coliseum (Dallas) | Sat, Jan 9, 2027, 2:15 PM ET | Moody Coliseum (Dallas) |
| Wed, Jan 13, 2027 |  vsCalifornia Golden BearsWeek 11KFC Yum! Center | Wed, Jan 13, 2027, 7:00 PM ET | KFC Yum! Center |
| Sat, Jan 16, 2027 |  @Syracuse OrangeWeek 11JMA Wireless Dome | Sat, Jan 16, 2027, 2:00 PM ET | JMA Wireless Dome |
| Tue, Jan 19, 2027 |  vsMiami HurricanesWeek 12KFC Yum! Center | Tue, Jan 19, 2027, 7:00 PM ET | KFC Yum! Center |
| Sat, Jan 23, 2027 |  vsBaylor BearsWeek 12Hinkle Fieldhouse | Sat, Jan 23, 2027, 4:00 PM ET | Hinkle Fieldhouse |
| Wed, Jan 27, 2027 |  @Boston College EaglesWeek 13Conte Forum | Wed, Jan 27, 2027, 7:00 PM ET | Conte Forum |
| Sat, Jan 30, 2027 |  @Georgia Tech Yellow JacketsWeek 13McCamish Pavilion | Sat, Jan 30, 2027, 12:00 PM ET | McCamish Pavilion |
| Tue, Feb 2, 2027 |  vsPittsburgh PanthersWeek 14KFC Yum! Center | Tue, Feb 2, 2027, 9:00 PM ET | KFC Yum! Center |
| Sat, Feb 6, 2027 |  vsWake Forest Demon DeaconsWeek 14KFC Yum! Center | Sat, Feb 6, 2027, 3:00 PM ET | KFC Yum! Center |
| Mon, Feb 8, 2027 | @North Carolina Tar HeelsWeek 15Dean E. Smith Center | Mon, Feb 8, 2027, 6:00 PM ET | Dean E. Smith Center |
| Sat, Feb 13, 2027 | vsSMU MustangsWeek 15KFC Yum! Center | Sat, Feb 13, 2027, 12:00 PM ET | KFC Yum! Center |
| Mon, Feb 15, 2027 |  @Virginia CavaliersWeek 16John Paul Jones Arena | Mon, Feb 15, 2027, 7:00 PM ET | John Paul Jones Arena |
| Sun, Feb 21, 2027 |  @Florida State SeminolesWeek 16Tucker Center | Sun, Feb 21, 2027, 4:00 PM ET | Tucker Center |
| Wed, Feb 24, 2027 |  vsDuke Blue DevilsWeek 17KFC Yum! Center | Wed, Feb 24, 2027, 7:00 PM ET | KFC Yum! Center |
| Tue, Mar 2, 2027 |  @NC State WolfpackWeek 18Lenovo Center | Tue, Mar 2, 2027, 7:00 PM ET | Lenovo Center |
| Sat, Mar 6, 2027 |  vsClemson TigersWeek 18KFC Yum! Center | Sat, Mar 6, 2027, 12:00 PM ET | KFC Yum! Center |
Louisville Cardinals Schedule 2026-2027: Dates, Times, TV and Results